Evaluation of MTAP immunohistochemistry loss of expression in ovarian serous borderline tumors as a potential marker for prognosis and progression

Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer
Serous borderline tumors (SBT) are the commonest subtype of ovarian borderline tumors with wonderful scientific course. Beside BRAF and KRAS mutations, copy quantity alterations (CNA), notably lack of chromosome 9p21 locus which leads to deletion of genes CDKN2A and MTAP, have been urged to be concerned in illness development. MTAP immunohistochemistry just lately has been launched for mesothelioma as a dependable surrogate marker for the homozygous deletion of chromosome 9p21 locus. Due to this fact, within the present research, we aimed to guage the MTAP lack of expression in serous borderline tumors and low-grade serous carcinomas to establish if it may be used as a marker for prognosis and development.
Eighty-four complete instances of ovarian serous lesions, together with 21 instances of serous cystadenomas, 21 instances of serous borderline tumors, 12 instances of low-grade serous carcinomas and 30 instances of high-grade serous carcinomas have been chosen. MTAP immunohistochemistry was carried out on the consultant blocks and cytoplasmic staining was used for interpretation. The instances have been labeled as optimistic (retained) if MTAP confirmed cytoplasmic granular staining and unfavourable (lack of expression) if unfavourable cytoplasmic staining was noticed within the presence of optimistic inside management.
Ten of 21 instances of serous borderline tumors confirmed lack of MTAP expression (48%). Amongst these, 7 instances have been bilateral, 2 instances had micropapillary options, one case had supraclavicular and cervical lymph node involvement by serous borderline tumor and a couple of instances had development to low-grade serous carcinoma, together with considered one of micropapillary tumors. Additionally eight out of 12 instances of LGSCs confirmed MTAP lack of expression (66%). Solely four of 30 instances of high-grade serous carcinomas (13%) and not one of the serous cystadenoma instances confirmed lack of expression of MTAP.
 To our data, that is the primary description of MTAP immunohistochemistry in serous borderline tumors and low-grade serous carcinomas. Our research was restricted attributable to small pattern measurement. Nonetheless, it confirmed an affiliation between MTAP lack of expression and hostile scientific habits in ovarian serous borderline tumors. This helps the position for additional investigations in bigger collection to guage the position of MTAP stain as a prognostic marker in these neoplasms. Nonetheless, they’ll recur or progress to low-grade serous carcinoma (LGSC) in a small proportion of the instances.

A descriptive research of human papilloma virus in higher aero-digestive squamous cell carcinoma at Uganda most cancers institute assessed by P16 immunohistochemistry

Most cancers burden in sub-Saharan Africa is on the rise with one-third of cancers estimated to be attributable to infectious brokers. Head and neck squamous cell most cancers (HNSCC) is the sixth commonest malignancy in sub-Saharan Africa and contains tumors within the Higher Aero-digestive Tract (UADT). The established threat elements are tobacco and alcohol publicity with a current recognition of the position of Human Papilloma Virus (HPV). The HPV associated HNC is seen predominantly within the oropharynx, presents at a youthful age and has a greater prognosis.
With a quickly growing incidence of those cancers within the developed world, it was essential to review HPV in HNC in Uganda. The HPV might be detected utilizing P16 immunohistochemistry as a surrogate marker thus making it appropriate for screening. The research geared toward establishing the presence of HPV and the generally affected websites in UADT squamous cell carcinoma (SCC) at Uganda Most cancers Institute (UCI) utilizing P16 immunohistochemistry. This was a cross sectional research wherein 59 sufferers with histologically confirmed SCC from the oral cavity, oropharynx, larynx and hypopharynx have been recruited.
These sufferers’ demographics and scientific information have been collected. Tissue sections from retrieved histology samples have been stained by Haematoxylin and Eosin to reconfirm SCC. Subsequently, P16 expression was decided utilizing P16 immunohistochemistry. together with among the pillars of antibody validation from Uhlen et al. 2016, for example of a rigorous strategy to construct antibody-based checks for each primary and translational science labs and for the clinic.
 Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer

Scientific Functions of Immunohistochemistry in Germ Cell Tumors in Males

Germ cell tumors (GCT) in males comprise of tumor subtypes with distinct histomorphologies, genetic and genomic alterations, and scientific habits. Immunohistochemical (IHC) markers, together with many newly described nuclear transcription elements, are sometimes utilized in difficult instances to reach at an accurate analysis and classification, and to determine germ cell origin for metastatic tumors. Nonetheless, there is no such thing as a established position for IHC markers in prognosis and remedy response prediction in GCTs. This chapter briefly critiques the scientific utility of IHC in analysis and classification of GCTs, together with technical features of performing IHC and scientific purposes of generally used IHC markers within the workup of frequent and clinically related diagnostic eventualities.

Antibodies play a vital position in primary analysis and scientific decision-making. Nonetheless, there aren’t any standardized algorithms or pointers to make sure their accuracy and validity. There have been efforts to generate consensus, however, except for scientific labs, antibody validation stays variable within the literature and generally in scientific observe. Right here we deal with immunohistochemistry, an instance of a scientific and scientific device the place validation of antibodies is crucial. We describe a protocol that we use to validate antibodies particularly for immunohistochemistry,

A case of mammary myofibroblastoma diagnosed with cytomorphological, cell block and immunohistochemistry findings

A case of mammary myofibroblastoma diagnosed with cytomorphological, cell block and immunohistochemistry findings

The interpretation of outcomes on immunostained cell-block sections needs to be in contrast with the cumulative printed knowledge derived predominantly from formalin-fixed paraffin-embedded (FFPE) tissue sections. Due to this, it is very important acknowledge that the fixation and processing protocol shouldn’t be totally different from the routinely processed FFPE surgical pathology tissue. Publicity to non-formalin fixatives or reagents could intervene with the diagnostic immunoreactivity sample. The immunoprofile noticed on such cell-blocks, which aren’t processed in a fashion just like the surgical pathology specimens, will not be consultant leading to aberrant outcomes.

The sphere of immunohistochemistry (IHC) is advancing constantly with the standardization of many immunomarkers. Quite a lot of technical advances comparable to multiplex IHC with refined methodologies and automation is growing its position in medical purposes. The latest addition of rabbit monoclonal antibodies has additional improved sensitivity. As in comparison with the mouse monoclonal antibodies, the rabbit monoclonal antibodies have 10 to 100 fold greater antigen affinity. Many of the situations contain the analysis of coordinate immunostaining patterns in cell-blocks with comparatively scant diagnostic materials with out correct orientation which is normally retained in a lot of the surgical pathology specimens.

These challenges are addressed if cell-blocks are ready with some devoted methodologies comparable to NextGen CelBloking™ (NGCB) kits. Cell-blocks ready by NGCB kits additionally facilitate the straightforward utility of the SCIP (subtractive coordinate immunoreactivity sample) strategy for correct analysis of coordinate immunoreactivity. Varied cell-block and IHC-related points are mentioned intimately. Pericytes are present in all vascularized organs and are outlined anatomically as perivascular cells that intently encompass endothelial cells in capillaries and microvessels and are embedded inside the similar basement membrane.

mTOR Pathway Activation Assessed by Immunohistochemistry in Cervical Biopsies of HPV-associated Endocervical Adenocarcinomas (HPVA): Correlation With Silva Invasion Patterns

The Silva sample of invasion, not too long ago launched to stratify sufferers in danger for lymph node metastases in human papillomavirus-associated endocervical adenocarcinomas (HPVAs), can solely be assessed in cone and loop electrosurgical excision process excisions with adverse margins or in a hysterectomy specimen. Earlier research discovered associations between harmful stromal invasion patterns (Silva patterns B and C) and mutations in genes concerned within the MEK/PI3K pathways that activate the mammalian goal of rapamycin (mTOR) pathway. The first intention of this research was to make use of cervical biopsies to find out whether or not markers of mTOR pathway activation affiliate with aggressive invasion patterns in matched excision specimens.

The standing of the markers in small biopsy specimens ought to enable us to foretell the ultimate and biologically related sample of invasion in a resection specimen. With the ability to predict the ultimate sample of invasion is necessary, since prediction as Silva A, for instance, would possibly encourage conservative medical administration. If the sample within the resection specimen is B with lymphovascular invasion or C, additional surgical procedure could be carried out 34 HPVA biopsies have been evaluated for expression of pS6, pERK, and HIF1α. Immunohistochemical stains have been scored semiquantitatively, starting from Zero to 4+ with scores 2 to 4+ thought of constructive, and Silva sample was decided in follow-up excisional specimens.

Silva patterns acknowledged in excisional specimens have been distributed as follows: sample A (n=8), sample B (n=4), and sample C (n=22). Statistically vital associations have been discovered evaluating pS6 and pERK immunohistochemistry with Silva sample (P=0.034 and 0.05, respectively). Of the three markers examined, pERK was essentially the most highly effective for distinguishing between sample A and patterns B and C (P=0.026; odds ratio: 6.75, 95% confidence interval: 1.111-41.001). Though the adverse predictive values have been disappointing, the constructive predictive values have been encouraging: 90% for pERK, 88% for pS6 and 100% for HIF1α. mTOR pathway activation assessed by immunohistochemistry in cervical biopsies of HPVA correlate with Silva invasion patterns.

 A case of mammary myofibroblastoma diagnosed with cytomorphological, cell block and immunohistochemistry findings

Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Actual-Time PCR-Based mostly Idylla Check

The BRAF V600E mutation is a vital oncological goal in sure central nervous system (CNS) tumors, for which a potential utility of BRAF-targeted remedy grows constantly. Within the current research, we intention to find out the prevalence of BRAF V600E mutations in a sequence of ganglioglioma (GG) and pilocytic astrocytoma (PA) circumstances. Concurrently, we determined to confirm whether or not the mix of absolutely automated tests-BRAF-VE1 immunohistochemistry (IHC) and Idylla BRAF mutation assay-may be helpful to precisely predict it within the case of specified CNS tumors.

The research included 49 formalin-fixed, paraffin-embedded tissues, of which 15 have been GG and 34 PA. Immunohistochemistry with anti-BRAF V600E (VE1) antibody was carried out on tissue sections utilizing the VentanaBenchMark ULTRA platform. All constructive or equivocal circumstances on IHC and chosen adverse ones have been additional assessed utilizing the Idylla BRAF mutation assay coupled with the Idylla platform. The BRAF-VE1 IHC was constructive in 6 (6/49; 12.3%) and adverse in 39 samples (39/49; 79.6%). The interpretation of immunostaining outcomes was sophisticated in Four circumstances, of which 1 examined constructive for the Idylla BRAF mutation assay. Subsequently, the general positivity fee was 14.3%.

Streptavidin

SE497 5mg
EUR 224

Streptavidin

R-1100 1 mg
EUR 197.9
Description: The best epigenetics products

Streptavidin

E61I01602 100ug
EUR 343

Streptavidin

S0902-002 2mg
EUR 223

Streptavidin

S0902-003 10mg
EUR 421

Streptavidin

abx670356-5mg 5 mg
EUR 467

Streptavidin

7-06550 2mg Ask for price

Streptavidin

7-06551 10mg Ask for price

Streptavidin

7-06552 100mg Ask for price

Streptavidin

RP-1531 5 mg
EUR 164

Streptavidin

STVF-50 50 ug
EUR 115

Streptavidin

STVPE-50 50 ug
EUR 115

Streptavidin

FNSA-0001 500 uL
EUR 324
Description: Streptavidin secondary antibody

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Streptavidin Fluorescent Particle Kit

SVFA-2552--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFA-2558--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFB-2552--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Fluorescent Particle Kit

SVFB-2558--6K 6x1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin, Streptavidin Recombinant Protein, His Tag

PROTP22629-1 Regular: 20ug
EUR 317
Description: Recombinant Streptomyces Avidinii Streptavidin produced in E.Coli is a single, non-glycosylated polypeptide chain (25-183) containing a total of 167 amino acids and having a molecular mass of 17kDa. The Streptavidin protein is fused to an 8 aa N-terminal His-Tag and purified by proprietary chromatographic techniques.

Streptavidin Antibody

1-CSB-PA332849YA01SNO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Streptavidin. Recognizes Streptavidin from Streptomyces avidinii. This antibody is Unconjugated. Tested in the following application: ELISA

Streptavidin Antibody

1-CSB-PA18194A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Streptavidin. Recognizes Streptavidin from Streptomyces avidinii. This antibody is Unconjugated. Tested in the following application: ELISA

Streptavidin/HRP

F099 12 ml
EUR 257
Description: Streptavidin/HRP by Cygnus Technologies is available in Europe via Gentaur.

Streptavidin protein

PROTP22629 Regular: 10mg
EUR 317
Description: Streptavidin is a protein produced by Streptomyces avidinii and isolated by purification from fermentation broth. The pure, homogeneous protein shows predominantly one single band in SDS PAGE. Streptavidin consists of 4 identical subunits, each bearing an active binding site for biotin. Streptavidin has a molecular weight of 55kDa.

Streptavidin -HRP

E61I01602H 100ug
EUR 343

Streptavidin Antibody

21155-05011 150 ug
EUR 217

Streptavidin, Lyophilized

S0819-002 2mg
EUR 286

Streptavidin, Lyophilized

S0819-010 10mg
EUR 415

Streptavidin, CF514

29081 1mg
EUR 253
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin Antibody

20-abx319856
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Streptavidin Antibody

20-abx339012
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Streptavidin (APC)

abx670347-100tests 100 tests
EUR 398

Streptavidin (FITC)

abx670348-1mg 1 mg
EUR 398

Streptavidin (RPE)

abx670349-1ml 1 ml
EUR 398

Streptavidin (HRP)

abx670350-1mg 1 mg
EUR 398

Streptavidin (AP)

abx670351-1mg 1 mg
EUR 551

Streptavidin (FITC)

abx670352-1mg 1 mg
EUR 495

Streptavidin (AP)

abx670353-1ml 1 ml
EUR 495

Streptavidin (HRP)

abx670354-1ml 1 ml
EUR 467

Streptavidin Protein

abx061011-1mg 1 mg
EUR 286

Recombinant Streptavidin

7-06553 5mg Ask for price

Recombinant Streptavidin

7-06554 20mg Ask for price

Recombinant Streptavidin

7-06555 1gr Ask for price

Streptavidin Antibody

abx020705-1mg 1 mg
EUR 648

Streptavidin Protein

20-abx261434
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Streptavidin Protein

abx261783-1gr 1 gr
EUR 4128

Streptavidin Protein

20-abx261783
  • EUR 328.00
  • EUR 230.00
  • 20 mg
  • 5 mg

Streptavidin Protein

20-abx263128
  • EUR 1344.00
  • EUR 328.00
  • EUR 230.00
  • 100 mg
  • 10 mg
  • 2 mg

Streptavidin Polystyrene

SVP-1000-4 4 mL
EUR 472
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin (PE)

80R-2357 250 ug
EUR 165
Description: Purified Streptavidin conjugated to Phycoerythrin

Streptavidin (Cy3)

XG-6187Cy3 0.5 mg
EUR 424.1
Description: Streptavidin (Cy3)

Streptavidin (FITC)

XG-6187F 0.5 mg
EUR 424.1
Description: Streptavidin (FITC)

Streptavidin (HRP)

XG-6187HRP 0.5 mg
EUR 424.1
Description: Streptavidin (HRP)

Streptavidin antibody

10R-S118a 1 mg
EUR 489
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-S118b 1 mg
EUR 457
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-S118c 1 mg
EUR 392
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

10R-1103 100 ul
EUR 316
Description: Mouse monoclonal Streptavidin antibody

Streptavidin antibody

20R-3017 2 mL
EUR 503
Description: Rabbit polyclonal Streptavidin antibody

Streptavidin protein

30C-CE0301 10 mg
EUR 547
Description: Purified homogeneous preparation of Streptavidin protein

Core Streptavidin

7936-1
EUR 142

Core Streptavidin

7936-10
EUR 528

Core Streptavidin

7936-5
EUR 316

Streptavidin - FITC

P1498-10 10 mg
EUR 171

Streptavidin - FITC

P1498-50 50 mg
EUR 530

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132

AP-streptavidin conjugate [Streptavidin-alkaline phosphatase conjugate]

16921 1 mg
EUR 176

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132

Streptavidin Blue Array Particle Kit

SVPAK-5067--10K 10 mL
EUR 994
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Blue Array Particle Kit

SVPAK-5067--5A 5X1 mL
EUR 588
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Streptavidin Blue Array Particle Kit

SVPAK-5067--5B 5X1 mL
EUR 588
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941

Recombinant Streptavidin (SA)

4-RPX259Ge01
  • EUR 277.41
  • EUR 177.00
  • EUR 765.28
  • EUR 321.76
  • EUR 543.52
  • EUR 248.00
  • EUR 1763.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Streptavidin expressed in: E.coli

Recombinant Streptavidin (SA)

4-RPX259Ge02
  • EUR 277.41
  • EUR 177.00
  • EUR 765.28
  • EUR 321.76
  • EUR 543.52
  • EUR 248.00
  • EUR 1763.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Streptavidin expressed in: E.coli

RPE-streptavidin conjugate

16900 100 ug
EUR 132

RPE-streptavidin conjugate

16901 1 mg
EUR 306

APC-streptavidin conjugate

16902 100 ug
EUR 176

PerCP-streptavidin conjugate

16905 100 ug
EUR 219

FITC-streptavidin conjugate

16910 1 mg
EUR 176

HRP-streptavidin conjugate

16920 1 mg
EUR 176

Streptomyces avidinii Streptavidin

1-CSB-YP332849SNO
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Streptomyces avidinii Streptavidin expressed in Yeast

Streptavidin-Peroxidase , 5ML

C203-5ML 5ML
EUR 268

Streptomyces avidinii Streptavidin

1-CSB-EP332849SNO
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Streptomyces avidinii Streptavidin expressed in E.coli

Streptavidin Recombinant Protein

PROTP22629-2 Regular: 20mg
EUR 317
Description: Streptavidin Streptomyces Avidinii Recombinant produced in E.Coli. ;The molecular weight per tetramer is approximately 52kDa.

Streptavidin: HRP Conjugate

R-1098 0.5 ml
EUR 181.95
Description: Ask the seller for details

ProMag HP Streptavidin

PMS3-HP-1 1 ml
EUR 221.4
Description: ProMag HP Streptavidinsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag HP Streptavidin

PMS3HP-10 10 ml
EUR 929.36
Description: ProMag HP Streptavidinsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag HP Streptavidin

PMS3HP-2 2 ml
EUR 330.15
Description: ProMag HP Streptavidinsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag HP Streptavidin

PMS3HP-5 5 ml
EUR 569.4
Description: ProMag HP Streptavidinsuitable for use in assay developmen. This item is supplied as suspension in water.

Streptavidin Magnetic Beads

HY-K0208 5 mL
EUR 538

Anti-Streptavidin antibody

STJ16100613 1 mL
EUR 478

Streptavidin, HRP conjugated

S0900-001 1mg
EUR 300

Streptavidin, Phosphatase conjugated

S0901-001 1mg
EUR 421

Streptavidin, CF532 conjugate

29030 1mg
EUR 259
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF350 conjugate

29031 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF405S conjugate

29032 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF405M conjugate

29033 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF488A conjugate

29034 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF568 conjugate

29035 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF594 conjugate

29036 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF633 conjugate

29037 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF555 conjugate

29038 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF647 conjugate

29039 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF660R conjugate

29040 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF640R conjugate

29041 1mg
EUR 245
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, CF543 conjugate

29043 1mg
EUR 259
Description: Minimum order quantity: 1 unit of 1mg

Streptavidin, HRP conjugate

29049 1mg
EUR 234
Description: Minimum order quantity: 1 unit of 1mg

This included 2 circumstances of GG and 5 circumstances of PA. Our research discovered that BRAF V600E mutations are reasonably frequent in PA and GG and that for these tumor entities, IHC VE1 is appropriate for screening functions, however all adverse, equivocal, and weak constructive circumstances ought to be additional examined with molecular biology methods, of which the Idylla system appears to be a promising device. They’ve been proven to have various physiological and pathological capabilities together with regulation of blood stress, and tissue regeneration and scarring. Basic to understanding the position these cells play in these various processes is the flexibility to precisely establish and localize them in vivo. To do that, we’ve developed multicolor immunohistochemistry protocols described on this chapter.

Micronodular thymic carcinoma with lymphoid hyperplasia: relevance of immunohistochemistry with a small panel of antibodies for diagnosis-a RYTHMIC study

Micronodular thymic carcinoma with lymphoid hyperplasia: relevance of immunohistochemistry with a small panel of antibodies for diagnosis-a RYTHMIC study

Micronodular thymic carcinoma with lymphoid hyperplasia (MNTCLH) is a uncommon type of thymic carcinoma. We current the expertise of RYTHMIC, the French nationwide community dedicated to the remedy of thymic epithelial tumors by multidisciplinary tumor boards with a assessment of all tumors by pathologists for classification and staging. Six circumstances of MNTCLH had been recognized throughout a assessment of 1007 thymic epithelial tumors. Histologically, epithelial cells with atypia and mitoses shaped micronodules that had been surrounded by an plentiful lymphoid background with follicles.

There was neither apparent fibro-inflammatory stroma nor necrosis. Spindle cells areas had been widespread. Preliminary prognosis was micronodular thymoma in two circumstances, mobile atypia being neglected, eclipsed by the micronodular sample. Immunohistochemistry with a panel of 5 antibodies confirmed that cytokeratins (AE1-AE3) and p63-positive epithelial cells additionally expressed CD5 and that there was no TdT-positive cells inside the tumors. CD20 highlighted the lymphoid hyperplasia. Moreover epithelial cells additionally expressed CD117 and diffusely Glut 1.

Twenty-seven micronodular thymomas with lymphoid stroma recognized throughout the identical interval didn’t present the CD5 and CD117 positivities seen in MNTCLH and contained TdT-positive lymphocytes. Three of the 6 sufferers with MNTCLH had adjuvant radiotherapy. Three sufferers with follow-up data had been alive with out recurrence at 38, 51, and 95 months. Our research exhibits that immunohistochemistry, corresponding to that used within the RYTHMIC community with a small panel of antibodies, could simply assist to substantiate the right prognosis of MNTCLH, a uncommon and low-aggressive type of thymic carcinoma, and keep away from the misdiagnosis of micronodular thymoma.

Immunohistochemistry evaluation reveals lysyl oxidase-like Three as a novel prognostic marker for major melanoma

Lysyl oxidase-like 3 (LOXL3) is an extracellular enzyme concerned within the synthesis of collagen and elastin, and it has been reported to advertise melanoma cell proliferation and invasion in vitro. Nevertheless, the expression degree of LOXL3 at totally different phases of melanocytic lesions and the function of LOXL3 in melanoma pathogenesis stay unknown. Immunohistochemical staining of LOXL3 in a tissue microarray of 373 biopsies at totally different melanocytic phases was carried out. The correlation between LOXL3 expression and affected person survival was examined utilizing Kaplan-Meier survival evaluation. Univariate and multivariate Cox regression analyses had been carried out to check the hazard ratios.

The tissue microarray research revealed that stronger expression of LOXL3 protein was discovered at extra superior melanocytic phases (P < 0.0001; χ2 check). Elevated LOXL3 expression was related to enhanced tumor thickness and mitosis. Survival evaluation confirmed considerably worsened prognosis in major melanoma sufferers when the LOXL3 expression degree was increased (P = 0.043; log-rank check). Multivariate Cox regression evaluation additional confirmed that LOXL3 expression is a prognostic issue for major melanoma affected person survival (P = 0.04). LOXL3 expression is positively correlated with tumor development and invasion, and its overexpression is related to worse prognosis of major melanoma sufferers.

LOXL3 can function a prognostic marker to assist establish major melanoma sufferers at increased dangers of demise. Seven monoclonal mouse and rabbit antibodies had been optimised utilizing formalin-fixed paraffin embedded (FFPE) human tissue blocks. 4um sections of FFPE block had been stained utilizing the Roche Ventana XT or Ventana ULTRA IHC automated analysers. This research modified producer advisable protocols through the use of a singular antigen retrieval methodology, including an amplification step, various major antibody incubation occasions, in addition to utilizing the Roche Ventana Ultraview detection system.

 Micronodular thymic carcinoma with lymphoid hyperplasia: relevance of immunohistochemistry with a small panel of antibodies for diagnosis-a RYTHMIC study

Mast Cell Tumors and Histiocytomas in Home Goats and Diagnostic Utility of CD117/c-Package and Iba1 Immunohistochemistry

Cutaneous spherical cell tumors in goats current a diagnostic problem. On this article, we offer an outline of caprine cutaneous mast cell tumors (MCT) and histiocytomas, and report on the validation of anti-human antibodies to CD117/KIT and Iba1 by immunohistochemistry on a variety of caprine tissues. Cells immunolabeled for CD117/KIT included resident mast cells in regular lung and pores and skin, interstitial cells of Cajal (gut), and neuronal cell our bodies (mind). Cells immunolabeled for Iba1 included resident macrophages in lots of tissues together with regular lung, dendritic cells (hemolymphatic tissues), Kupffer cells, and microglia.

Of 5 cutaneous MCT, just one had metachromasia of cytoplasmic granules; nonetheless, neoplastic cells of all 5 MCT had constructive immunolabeling for CD117/KIT. The CD117/KIT immunolabeling sample was predominately focal paranuclear in Three circumstances, and cytoplasmic or membranous in 1 case every. Two histiocytomas had been recognized and had sturdy constructive immunolabeling for Iba1 however not CD117/KIT. All 7 cutaneous spherical cell tumors described herein occurred in goats lower than four years of age; the two cutaneous histiocytomas had been in goats lower than 14 months of age.

Mouse Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Mu-96T 96T
EUR 415
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Mu-48Tests 48 Tests
EUR 321

Mouse Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Mu-96Tests 96 Tests
EUR 438

Ibrutinib drug-Human IgG Conjugate

IBT17-IgG 100 ug
EUR 529

Monoclonal Anti-phosphoserine IgG-Biotinylated

PSER12-BTN 100 ul
EUR 408

Biotinylated goat anti-mouse IgG (H+L)

16729 1 mg
EUR 176

Monoclonal Anti-Mouse C1q protein IgG biotinylated

C1Q13-MB 50 ug
EUR 408

Mouse Monoclonal Anti-Human CD8-biotinylated IgG

AB-13410 100 ug
EUR 347

Mouse Monoclonal Anti-Human CD3-biotinylated IgG

AB-13810 100 ug
EUR 347

Mouse Monoclonal Anti-Human CD4-biotinylated IgG

AB-16710 100 ug
EUR 347

Rabbit Anti-Mouse AXL protein IgG-Biotinylated

AXL11-BTN 100 ul
EUR 529

Mouse Monoclonal Anti-Human AXL protein IgG-Biotinylated

AXL13-BTN 100 ul
EUR 529

Mouse monoclonal anti-human Erythropoietin (EPO) IgG-Biotinylated

EPO11-B 50 tests
EUR 347

Goat Anti-Protein-A IgG-biotinylated

PRTA12-BTN 0.1 ml
EUR 384

Rabbit anti-Human CD40 IgG, Biotinylated

CD4011-BTN 50 ug
EUR 518

Sheep Anti-rat albumin IgG, biotinylated

ALBR12-BTN 50 ug
EUR 384

Immunoglobulin G (IgG) Polyclonal Antibody (Mouse), Biotinylated

4-PAA544Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin G (IgG). This antibody is labeled with Biotin.

Genorise® Biotinylated Mouse IgG polyclonal antibody

GR138001 50 µg
EUR 398

Anti-Mouse IgG antibody

STJ16100623 1 mL
EUR 704

Anti-Mouse IgG antibody

STJ16100624 1 mL
EUR 858

Anti-Mouse IgG antibody

STJ16100625 1 mL
EUR 871

Anti-Mouse IgG antibody

STJ16100626 1 mL
EUR 1489

Anti-Mouse IgG antibody

STJ16101228 1 mg
EUR 191

Anti-Mouse IgG antibody

STJ16101229 1.2 mg
EUR 229

Anti-Mouse IgG antibody

STJ16101230 1.2 mg
EUR 282

Anti-Mouse IgG antibody

STJ16101367 1 mg
EUR 214

Anti-Mouse IgG antibody

STJ16101368 1.2 mg
EUR 257

Anti-Mouse IgG antibody

STJ16101369 1.2 mg
EUR 306

Bovine Immunoglobulin G (IgG) ELISA Kit

RD-IgG-b-48Tests 48 Tests
EUR 453

Bovine Immunoglobulin G (IgG) ELISA Kit

RD-IgG-b-96Tests 96 Tests
EUR 625

Porcine Immunoglobulin G (IgG) ELISA Kit

RD-IgG-p-48Tests 48 Tests
EUR 453

Porcine Immunoglobulin G (IgG) ELISA Kit

RD-IgG-p-96Tests 96 Tests
EUR 625

Rat Immunoglobulin G (IgG) ELISA Kit

RD-IgG-Ra-48Tests 48 Tests
EUR 314

Rat Immunoglobulin G (IgG) ELISA Kit

RD-IgG-Ra-96Tests 96 Tests
EUR 428

Bovine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-b-48T 48T
EUR 456
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Bovine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-b-96T 96T
EUR 590
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Canine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-c-48T 48T
EUR 441
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Canine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-c-96T 96T
EUR 570
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Eq-48T 48T
EUR 360
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Eq-96T 96T
EUR 457
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-g-48T 48T
EUR 464
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-g-96T 96T
EUR 601
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Hu-48T 48T
EUR 239
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Hu-96T 96T
EUR 292
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-p-48T 48T
EUR 456
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-p-96T 96T
EUR 590
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Ra-48T 48T
EUR 334
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Ra-96T 96T
EUR 422
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Rb-48T 48T
EUR 337
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Rb-96T 96T
EUR 426
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-b-48Tests 48 Tests
EUR 473

Bovine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-b-96Tests 96 Tests
EUR 654

Canine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-c-48Tests 48 Tests
EUR 455

Canine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-c-96Tests 96 Tests
EUR 629

Equine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Eq-48Tests 48 Tests
EUR 358

Equine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Eq-96Tests 96 Tests
EUR 490

Goat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-g-48Tests 48 Tests
EUR 482

Goat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-g-96Tests 96 Tests
EUR 667

Human Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Hu-48Tests 48 Tests
EUR 216

Human Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Hu-96Tests 96 Tests
EUR 287

Porcine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-p-48Tests 48 Tests
EUR 473

Porcine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-p-96Tests 96 Tests
EUR 654

Rat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Ra-48Tests 48 Tests
EUR 328

Rat Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Ra-96Tests 96 Tests
EUR 447

Rabbit Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Rb-48Tests 48 Tests
EUR 331

Rabbit Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Rb-96Tests 96 Tests
EUR 451

Biotinylated goat anti-rabbit IgG (H+L)

16794 1 mg
EUR 176

Monoclonal Anti-Human C1q protein IgG biotinylated

C1Q12-MB 50 ug
EUR 408

Monoclonal Anti-Human Leptin Protein IgG-Biotinylated

LEP32-BTN 50 ug
EUR 408

Rabbit Anti-Human AXL protein IgG-Biotinylated

AXL12-BTN 100 ul
EUR 529

Mouse anti-nucleosome antibody IgG(AnuA-IgG)ELISA Kit

GA-E0424MS-48T 48T
EUR 336

Mouse anti-nucleosome antibody IgG(AnuA-IgG)ELISA Kit

GA-E0424MS-96T 96T
EUR 534

Mouse anti-cardiolipin antibody IgG(ACA-IgG)ELISA Kit

GA-E0455MS-48T 48T
EUR 336

Mouse anti-cardiolipin antibody IgG(ACA-IgG)ELISA Kit

GA-E0455MS-96T 96T
EUR 534

Mouse anti-cardiolipin antibody IgG(ACA-IgG)ELISA Kit

QY-E20114 96T
EUR 361

Mouse ACA-IgG(anti-Cardiolipin Antibody IgG) ELISA Kit

EM0274 96T
EUR 476.25
Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Mus ;Sensitivity: 1.875 ng/ml

Mouse anti-cardiolipin antibody IgG,ACA-IgG ELISA Kit

CN-02647M1 96T
EUR 478

Mouse anti-cardiolipin antibody IgG,ACA-IgG ELISA Kit

CN-02647M2 48T
EUR 329

Mouse anti cardiolipin antibody IgG,ACA IgG ELISA kit

E03A2051-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgG,ACA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti cardiolipin antibody IgG,ACA IgG ELISA kit

E03A2051-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgG,ACA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti cardiolipin antibody IgG,ACA IgG ELISA kit

E03A2051-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgG,ACA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Gu-48T 48T
EUR 315
Description: A competitive inhibition quantitative ELISA assay kit for detection of Guinea pig Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Gu-96T 96T
EUR 396
Description: A competitive inhibition quantitative ELISA assay kit for detection of Guinea pig Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Gu-48Tests 48 Tests
EUR 305

Guinea pig Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Gu-96Tests 96 Tests
EUR 415

Biotinylated-Rat monoclonal Anti-Mouse Transferrin receptor1 (TfR1) IgG # 5

TFR17-M 100 ug
EUR 482

Mouse Monoclonal Anti-Zika Virus Envelope Protein (African) IgG-Biotinylated

ZENV12-BTN 100 ul
EUR 529

Mouse Monoclonal Anti-Zika Virus Envelope Protein (African) IgG-Biotinylated

ZENV13-BTN 100 ul
EUR 529

Mouse anti-Human IgG Antibody

abx015704-100ul 100 ul
EUR 411

Mouse Anti-Sheep IgG Antibody

abx023338-1mg 1 mg
EUR 592

Mouse Anti-Human IgG Antibody

abx023381-1mg 1 mg
EUR 439

Mouse anti-Cow IgG Antibody

abx401335-025mg 0.25 mg
EUR 592

Mouse anti-Cow IgG Antibody

abx401336-01mg 0.1 mg
EUR 453

Mouse anti-Cat IgG Antibody

abx401350-025mg 0.25 mg
EUR 676

Mouse anti-Cat IgG Antibody

abx401392-2ml 2 ml
EUR 606

Rabbit anti-Mouse IgG Antibody

abx401546-1mg 1 mg
EUR 328

Mouse Anti-Pig IgG antibody

STJ99550-100l 100 µl
EUR 81
Description: Unconjugated Mouse monoclonal to Pig IgG antibody

Mouse Anti-Pig IgG antibody

STJ99550-1mL 1 mL
EUR 396
Description: Unconjugated Mouse monoclonal to Pig IgG antibody

Mouse Anti-Monkey IgG antibody

STJ99551-100l 100 µl
EUR 91
Description: Unconjugated Mouse monoclonal to Monkey IgG antibody

Mouse Anti-Monkey IgG antibody

STJ99551-1mL 1 mL
EUR 514
Description: Unconjugated Mouse monoclonal to Monkey IgG antibody

Mouse anti Human IgG antibody

10R-1960 100 ul
EUR 241
Description: Mouse monoclonal human IgG antibody

ACA-IgG ELISA Kit| Mouse anti-Cardiolipin Antibody IgG ELISA Kit

EF012968 96 Tests
EUR 689

Mouse anti-cardiolipin antibody (IgG) ELISA Kit

CSB-E08646m-24T 1 plate of 24 wells
EUR 165
Description: Qualitative indirect ELISA kit for measuring Mouse anti-cardiolipin antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse anti-cardiolipin antibody (IgG) ELISA Kit

1-CSB-E08646m
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitative indirect ELISA kit for measuring Mouse anti-cardiolipin antibody (IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse anti-nuclear Antibody (IgG) ELISA Kit

CSB-E12912m-24T 1 plate of 24 wells
EUR 165
Description: QuantitativecaptureELISA ELISA kit for measuring Mouse anti-nuclear Antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse anti-nuclear Antibody (IgG) ELISA Kit

1-CSB-E12912m
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: QuantitativecaptureELISA ELISA kit for measuring Mouse anti-nuclear Antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse anti-nucleosome antibody (IgG) ELISA Kit

CSB-E14342m-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse anti-nucleosome antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse anti-nucleosome antibody (IgG) ELISA Kit

1-CSB-E14342m
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse anti-nucleosome antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Anti-OVA IgG Antibody Assay Kit

3011 1 kit
EUR 605.35
Description: Mouse Anti-OVA IgG Antibody Assay Kit

Mouse Anti-dsDNA IgG Antibody Assay Kit

3031 1 kit
EUR 567.65
Description: Mouse Anti-dsDNA IgG Antibody Assay Kit

Mouse Anti-ssDNA IgG Antibody Assay Kit

3041 1 kit
EUR 567.65
Description: Mouse Anti-ssDNA IgG Antibody Assay Kit

Mouse Anti-LPS IgG Antibody Assay Kit

6106 1 kit
EUR 553.15
Description: Mouse Anti-LPS IgG Antibody Assay Kit

Mouse Anti-SEB IgG Antibody Assay Kit

6214 1 kit
EUR 553.15
Description: Mouse Anti-SEB IgG Antibody Assay Kit

Mouse Anti-SEA IgG Antibody Assay Kit

6218 1 kit
EUR 553.15
Description: Mouse Anti-SEA IgG Antibody Assay Kit

Mouse Anti myocardial antibody IgG ELISA kit

E03A0560-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Anti myocardial antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti myocardial antibody IgG ELISA kit

E03A0560-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Anti myocardial antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti myocardial antibody IgG ELISA kit

E03A0560-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Anti myocardial antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti gliadin antibody (IgG) ELISA kit

E03A2073-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse anti gliadin antibody (IgG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti gliadin antibody (IgG) ELISA kit

E03A2073-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse anti gliadin antibody (IgG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti gliadin antibody (IgG) ELISA kit

E03A2073-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse anti gliadin antibody (IgG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti nucleosome antibody IgG ELISA kit

E03A0829-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Anti nucleosome antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti nucleosome antibody IgG ELISA kit

E03A0829-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Anti nucleosome antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti nucleosome antibody IgG ELISA kit

E03A0829-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Anti nucleosome antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Mouse Anti-cardiolipin antibody IgG (ACA-IgG)

KTE71511-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Mouse Anti-cardiolipin antibody IgG (ACA-IgG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Anti-cardiolipin antibody IgG (ACA-IgG)

KTE71511-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Mouse Anti-cardiolipin antibody IgG (ACA-IgG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Anti-cardiolipin antibody IgG (ACA-IgG)

KTE71511-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Mouse Anti-cardiolipin antibody IgG (ACA-IgG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Monoclonal Anti-Anthrax Protective antigen (PA83) IgG biotinylated

PA12-MB 50 ug
EUR 408

Goat Anti-lethal factor (B Anthracis) IgG-biotinylated

LF16-AB 50 ug
EUR 408

Mouse Anti-Pertussis toxin IgG (Anti-PT-IgG) ELISA Kit

abx055566-96tests 96 tests
EUR 668

Mouse Anti-Tetanus Toxoid IgG (anti-TT IgG) ELISA Kit

abx055567-96tests 96 tests
EUR 668

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

ExoAb Antibody Kit (CD9, CD63, CD81, Hsp70 antibodies, rabbit anti-human) with goat anti-rabbit HRP secondary antibody

EXOAB-KIT-1 25 ul each
EUR 627

Anti-IgG antibody

STJ16101012 100 µg
EUR 354

Anti-IgG antibody

STJ16101338 1 mL
EUR 361

Anti-IgG antibody

STJ16101474 1 mL
EUR 361

Anti-IgG antibody

STJ180131 0.1 ml
EUR 212

Anti-IgG antibody

STJ400110 1 mg
EUR 383
Description: Immunoglobulin G (IgG) is a monomeric immunoglobulin, built of two heavy chains and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Anti-IgG antibody

STJ400111 1 mg
EUR 383
Description: Immunoglobulin G (IgG) is a monomeric immunoglobulin, built of two heavy chains and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Biotinylated-Mouse Monoclonal Anti-Human FLK-1/VEGFR-2 IgG # 3

FLK13-MB 100 ug
EUR 408

Biotinylated-Mouse monoclonal Anti-Human Transferrin receptor 1 (TfR1) IgG # 4

TFR14-M 100 ug
EUR 482

Human anti-toxoplasma IgG antibody(anti-tox IgG)ELISA Kit

GA-E1863HM-48T 48T
EUR 289

Neither of the cutaneous histiocytomas recurred inside 24 months of surgical removing. Gastric stump most cancers (GSC) has distinct clinicopathological traits from major gastric most cancers. Nevertheless, the detailed molecular and pathological traits of GSC stay to be clarified due to its rarity. On this research, a set of tissue microarrays from 89 GSC sufferers was analysed by immunohistochemistry and in situ hybridisation. Programmed demise ligand 1 (PD-L1) was expressed in 98.9% of tumour-infiltrating immune cells (TIICs) and 6.7% of tumour cells (TCs). Epstein-Barr virus (EBV) was detected in 18 sufferers (20.2%). Probably the most ceaselessly mutated genes had been TP53 (42.0%) adopted by SMAD4 (18.0%) and PTEN (16.0%), all of that are tumour suppressor genes.

Harmonization across programmed death ligand 1 (PD-L1) assays for lung cancer by immunohistochemistry using noncontact alternating current electric field mixing

Harmonization across programmed death ligand 1 (PD-L1) assays for lung cancer by immunohistochemistry using noncontact alternating current electric field mixing
Immune checkpoint inhibitors (ICIs) are a promising advance within the therapy of sufferers with lung most cancers. Nonetheless, every ICI has been examined with an independently designed companion diagnostic assay that’s primarily based on a singular antibody. Consequently, the completely different trial-validated programmed demise ligand 1 (PD-L1) immunohistochemistry (IHC) assays shouldn’t be thought of interchangeable. Our intention was to check the efficiency of every out there PD-L1 antibody for its skill to precisely measure PD-L1 expression and to analyze the potential of harmonization throughout antibodies by means of using a brand new speedy IHC system, which makes use of noncontact alternating present (AC) mixing to attain extra secure staining.
First, 58 resected non-small cell lung most cancers (NSCLC) specimens had been stained utilizing three PD-L1 IHC assays (28-8, SP142, and SP263) to evaluate the harmonization achieved with AC mixing IHC. Second, specimens from 27 sufferers receiving ICIs for postoperative recurrent NSCLC had been stained utilizing the identical IHC technique to check the scientific efficiency of ICIs to PD-L1 scores. All sufferers obtained a tumor proportion rating (TPS) with the 22C3 companion diagnostic check.
Higher staining was achieved with the brand new AC mixing IHC technique than the traditional IHC in PD-L1-positive instances, and the interchangeability of some combos of assays was elevated in PD-L1-positive. As well as, AC mixing IHC offered extra acceptable general response charges for ICIs in all assays. Sixteen out of 85 tumors confirmed constructive staining representing 5% of FB tumors, 24% of CCS tumors and 47% of FM. In FB and CCS tumors, constructive staining was primarily encountered in atypical intraepidermal melanocytic proliferations and spitzoid neoplasms. The specificity of constructive PRAME staining was 95% and its concordance with the ultimate diagnostic interpretation was 75%.

Impression of Preanalytical Components on the Measurement of Tumor Tissue Biomarkers Utilizing Immunohistochemistry

Evaluation of formalin-fixed paraffin-embedded (FFPE) tissue by immunohistochemistry (IHC) is commonplace in scientific and analysis laboratories. Nonetheless, reviews recommend that IHC outcomes might be compromised by biospecimen preanalytical elements. The Nationwide Most cancers Institute’s Biospecimen Preanalytical Variables Program performed a scientific research to look at the potential results of delay to fixation (DTF) and time in fixative (TIF) on IHC utilizing 24 most cancers biomarkers. Variations in IHC staining, relative to controls with a DTF of 1 hr, had been noticed in FFPE kidney tumor specimens after a DTF of ≥2 hr.

Reductions in H-score and/or staining depth had been noticed for c-MET, p53, PAX2, PAX8, pAKT, and survivin, whereas will increase had been noticed for RCC1, EGFR, and CD10. Extended TIF of 72 hr resulted in considerably lowered H-scores of CD44 and c-Met in kidney tumor specimens, in contrast with controls with 12-hr TIF. An elevated likelihood of altered staining depth attributable to DTF was noticed for 9 antigens, whereas for extended TIF an elevated likelihood was noticed for one antigen.

Outcomes reported right here and elsewhere throughout tumor sorts and antigens assist limiting DTF to ≤1 hr when attainable and fixing tissues in formalin for 12-24 hr to keep away from confounding results of those preanalytical elements on IHC. The persistent an infection of high-risk human papillomavirus (HR-HPV) is among the most typical causes of cervical most cancers worldwide, and HPV kind 58 (HPV58) is the third most typical HPV kind in japanese Asia. The E7 oncoprotein is constitutively expressed in HPV58-associated cervical most cancers cells and performs a key function throughout tumorigenesis. This research aimed to evaluate the HPV58 E7 protein expression within the tissues of cervical most cancers and cervical intraepithelial neoplasia (CIN).

 Harmonization across programmed death ligand 1 (PD-L1) assays for lung cancer by immunohistochemistry using noncontact alternating current electric field mixing

NKX3.1 immunohistochemistry is very particular for the prognosis of mesenchymal chondrosarcomas: expertise within the Australian inhabitants

Mesenchymal chondrosarcoma (MC) is a uncommon sarcoma that usually arises in adolescents and younger adults and characteristically harbours a HEY1-NCOA2 gene fusion. A current research has proven that NKX3.1 immunohistochemistry (IHC) is very particular and delicate in MCs. NKX3.1 is a nuclear marker expressed in prostatic tissue and is broadly utilized in most laboratories to find out prostatic origin of metastatic tumours. Within the present research we investigated whether or not this stain can be utilized within the diagnostic workup of MC, as it could help in triaging instances for additional molecular testing, by assessing its expression in a cohort of MCs and in a large spectrum of sarcoma sorts.
Moreover, we aimed to elucidate if expression of NKX3.1 by MCs is expounded to androgen receptor (AR) expression. We recognized NKX3.1 constructive nuclear staining in 9 of 12 particular person sufferers of MC (n=20 of 25 samples when taking into consideration separate episodes). 4 of the 5 unfavorable specimens had been beforehand subjected to acid-based decalcification. NKX3.1 was unfavorable in 536 samples from 16 non-MC sarcomas derived from largely tissue microarrays (TMAs). Total, we recognized 80% sensitivity and 100% specificity for NKX3.1 IHC in MCs.

Immunohistochemistry Kit (OKRA00038)

OKRA00038 1 kit
EUR 805
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

Immunohistochemistry Kit (OKRA00039)

OKRA00039 1 kit
EUR 805
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

Immunohistochemistry Kit (OKRA00040)

OKRA00040 1 kit
EUR 805
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

BrdU/ Rat BrdU ELISA Kit

ELA-E1336r 96 Tests
EUR 886

Brdu

20-abx082348
  • EUR 189.00
  • EUR 300.00
  • 100 mg
  • 1 g

5-BrdU

HY-15910 5g
EUR 497

5-BrdU

B3589-1000 1 g
EUR 142
Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111.

5-BrdU

B3589-5.1 10 mM (in 1mL DMSO)
EUR 113
Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111.

5-BrdU

B3589-500 500 mg
EUR 108
Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111.

anti-BrdU

BROF-100T 100 test
EUR 537.5

BRDU antibody

10R-6763 1 ml
EUR 402
Description: Mouse monoclonal BRDU antibody

BRDU antibody

10R-7945 100 ug
EUR 370
Description: Mouse monoclonal BRDU antibody

BRDU antibody

10R-B121a 100 ug
EUR 445
Description: Mouse monoclonal BRDU antibody

BRDU antibody

20-BS17 250 ug
EUR 386
Description: Sheep polyclonal BRDU antibody

BRDU antibody

10R-2321 1 mL
EUR 601
Description: Mouse monoclonal BRDU antibody

BRDU antibody

10R-2356 1.5 mL
EUR 490
Description: Mouse monoclonal BRDU antibody

BRDU antibody

20R-BS001 250 ug
EUR 553
Description: Sheep polyclonal BRDU antibody

Sheep BrDU ELISA Kit

ESB0693 96Tests