Urticaria is a disorder affecting skin and mucosal tissues characterized by the occurrence of wheals, angioedema or both, the latter defining the urticaria-angioedema syndrome.
It is estimated that 12-22% of the general population has suffered at least one subtype of urticaria during life, but only a small percentage (estimated at 7.6-16%) has acute urticaria, because it is usually self-limited and resolves spontaneously without requiring medical attention.
This makes likely that its incidence is underestimated. The epidemiological data currently available on chronic urticaria in many cases are deeply discordant and not univocal, but a recent Italian study, based on the consultation of a national registry, reports a prevalence of chronic spontaneous urticaria of 0.02% to 0.4% and an incidence of 0.1-1.5 cases/1000 inhabitants/year.
We reviewed the recent international guidelines about urticaria and we described a methodologic approach based on classification, pathophysiology, impact on quality of life, diagnosis and prognosis, differential diagnosis and management of all the types of urticaria.
hInsulin TRF 50 |
IHTR1017-50 |
Mediomics |
1 Kit |
EUR 288 |
rIgG FRET 50 |
RI1024-50 |
Mediomics |
1 Kit |
EUR 266 |
mIgG TRF 50 |
MIGTR1020-50 |
Mediomics |
1 Kit |
EUR 288 |
TruStrip Sample Transfer Strips, 50-ul, 50/Pk (without sample tracking dye) |
STS-50-50 |
Alpha Diagnostics |
1 Pk |
Ask for price |
TruStrip Sample Transfer Strips, 50-ul, 50/Pk (with sample tracking dye) |
STSD-50-50 |
Alpha Diagnostics |
1 Pk |
Ask for price |
MTBK_20640-50 |
AR02-P0011-50 |
Abfrontier |
50ug |
EUR 727 |
Bridge-It L-Tryptophan 50 |
1-1-1001A |
Mediomics |
1 Kit |
EUR 266 |
Bridge-It L-MET 50 |
1-1-1005A |
Mediomics |
1 Kit |
EUR 266 |
FUNNEL, 50 MM, PP |
6120P-50 |
CORNING |
24/pk |
EUR 49 |
Description: Reusable Plastics; Reusable Funnels |
Rabies(Rab-50) Antibody |
BNUM0943-50 |
Biotium |
50uL |
EUR 395 |
Description: Primary antibody against Rabies(Rab-50), 1mg/mL |
Rv0351 (GrpE)-50 |
AR02-P0003-50 |
Abfrontier |
50ug |
EUR 173 |
Rv1009 (RpfB)-50 |
AR02-P0006-50 |
Abfrontier |
50ug |
EUR 727 |
Rv2450c (RpfE)-50 |
AR02-P0007-50 |
Abfrontier |
50ug |
EUR 727 |
Rv3875 (esxA)-50 |
AR02-P0008-50 |
Abfrontier |
50ug |
EUR 727 |
Rv2031c(HspX)-50 |
AR02-P0009-50 |
Abfrontier |
50ug |
EUR 727 |
Rv3131 (NfnB)-50 |
AR02-P0010-50 |
Abfrontier |
50ug |
EUR 727 |
ERLENMEYER FLASK, 50 ML, PP |
4985P-50 |
CORNING |
6/pk |
EUR 50 |
Description: Reusable Plastics; Reusable Erl Flasks |
ERLENMEYER FLASK, 50 ML, PMP |
4990P-50 |
CORNING |
6/pk |
EUR 54 |
Description: Reusable Plastics; Reusable Erl Flasks |
Rabbit THYROID MATURE 50 EA* |
41352-1 |
Pel-Freez |
50 EA |
EUR 305.34 |
Rv2769c (PE27 protein)-50 |
AR02-P0001-50 |
Abfrontier |
50ug |
EUR 295 |
TR-FRET Bridge-It SAM 50 |
TRF-1-1-1003A |
Mediomics |
1 Kit |
EUR 288 |
slingshot homolog 1 (SSH1)(MBP-his tagged)-50 |
AR09-P0023-50 |
Abfrontier |
50ug |
EUR 4597 |
DNA Gel Extraction Kit - 50 Columns |
31030-50 |
Biotium |
1kit |
EUR 155 |
Description: Minimum order quantity: 1 unit of 1kit |
Cytokeratin 5/8(C-50) Antibody |
BNUM0948-50 |
Biotium |
50uL |
EUR 395 |
Description: Primary antibody against Cytokeratin 5/8(C-50), 1mg/mL |
Super piggyBac Transposase expression vector (replaces PB200A-1), 50 rxns |
PB210PA-1 |
SBI |
10 ug |
EUR 508 |
|
RNAfection, RNA transfection reagent 50 ul |
MR750A-1 |
SBI |
50 ul |
EUR 210 |
|
TR-FRET Bridge-It L-Tryptophan 50 |
TRF-1-1-1001A |
Mediomics |
1 Kit |
EUR 288 |
TR-FRET Bridge-It L-MET 50 |
TRF-1-1-1005A |
Mediomics |
1 Kit |
EUR 288 |
MTBK 20620 (PE protein)-50 |
AR02-P0005-50 |
Abfrontier |
50ug |
EUR 830 |
Aflatoxin G2 |
A118-0.5MG |
TOKU-E |
0.5 mg |
EUR 157 |
Aflatoxin G2 |
A118-2.5MG |
TOKU-E |
2.5 mg |
EUR 473 |
M-phase inducer phosphatase 1 (CDC25A)(MBP-his tagged)-50 |
AR09-P0030-50 |
Abfrontier |
50ug |
EUR 698 |
TruStrip Sample Storage/Transportation Trays (5 trays/cluster; 10 clusters for 50 strips) for 15-50 ul strips |
STT5-50 |
Alpha Diagnostics |
1 Pk |
Ask for price |
Rv0350 (Heat Shock Protein 70)-50 |
AR02-P0002-50 |
Abfrontier |
50ug |
EUR 180 |
Rv2299c (Heat Shock Protein 90)-50 |
AR02-P0004-50 |
Abfrontier |
50ug |
EUR 222 |
Excision only piggyBac Transposase expression vector, 50 rxns |
PB220PA-1 |
SBI |
10 ug |
EUR 508 |
|
protein tyrosine phosphatase, non-receptor type 1 (PTPN1)(His tagged)-50 |
AR09-P0027-50 |
Abfrontier |
50ug |
EUR 141 |
Single channel mini-pipette (130 mm) 50 ul, autoclavable |
SCMP-50 |
Alpha Diagnostics |
1 |
EUR 92 |
Antigen Retrieval Solution, Citrate pH 6.0 (50 ml, 100X) |
ARS6-50 |
Alpha Diagnostics |
5 L |
EUR 286 |
Antigen Retrieval Solution, EDTA pH 8.0 (50 ml, 100X) |
ARS8-50 |
Alpha Diagnostics |
5 L |
EUR 286 |
PTPRF(His tagged) / LAR(His tagged)-50 |
AR09-P0002-50 |
Abfrontier |
50ug |
EUR 431 |
ExoQuick-CG cGMP-grade Exosome Isolation reagent (50 ml) |
EXOCG50A-1 |
SBI |
50 ml |
EUR 1181 |
|
Adrenomedullin (1-50), rat |
5-00619 |
CHI Scientific |
4 x 1mg |
Ask for price |
Antigen Retrieval Solution, Tris-EDTA pH 9.0 (50 ml, 100X) |
ARS9-50 |
Alpha Diagnostics |
5 L |
EUR 286 |
BasicExoRNA? Basic RNA extraction kit (Pre-isolated exosomes, 50 reactions) |
K1222-50 |
Biovision |
|
EUR 1219 |
PLGA poly(lactic-co-glycolic) acid); synthetic; (50% lactic and 50% glycolic acid, ~30-60 Kda) |
AV-2010-1 |
Alpha Diagnostics |
0.1 g |
EUR 189 |
Adrenomedullin (Adrenomedullin (ADM/AM, 11-50) (rat) |
SP-100047-1 |
Alpha Diagnostics |
1 mg |
EUR 529 |
AXYPREP MAG DYECLEAN KIT- 50 ML - 5000 PREPS |
MAG-DYECL-50 |
CORNING |
1/pk |
EUR 1068 |
Description: Bioscience Mag Beads; Magnetic Dye |
RESERVOIR, POLYPROPYLENE, 50 ML, V-BOTTOM, NONSTERILE, BULK |
RES-V-50 |
CORNING |
100/pk |
EUR 67 |
Description: Reservoirs; Reservoirs - Axygen |
slingshot homolog 3 (SSH3)(MBP-his tagged)-50 |
AR09-P0024-50 |
Abfrontier |
50ug |
EUR 696 |
Human IgG/RF-adsorbent (Adsorb 50 serum samples of 100 ul) |
RFAD11-50 |
Alpha Diagnostics |
50 tests |
EUR 164 |
DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 50 nm |
GCK-M-50 |
Creative Diagnostics |
1 kit |
EUR 757 |
DiagNano Fluorophore Labeled Gold Nanoparticles, 50 nm, Cellular Uptake |
GFL-50-CU |
Creative Diagnostics |
1mL |
EUR 1365 |
PTPRC(His tagged) / Human CD45 (LCA)(His tagged)-50 |
AR09-P0001-50 |
Abfrontier |
50ug |
EUR 219 |
PTPN5(MBP-his tagged) / STEP(MBP-his tagged)-50 |
AR09-P0003-50 |
Abfrontier |
50ug |
EUR 160 |
PTPN11(MBP-his tagged) / SHP2(MBP-his tagged)-50 |
AR09-P0004-50 |
Abfrontier |
50ug |
EUR 447 |
ACP1(MBP-his tagged) / LMPTP(MBP-his tagged)-50 |
AR09-P0005-50 |
Abfrontier |
50ug |
EUR 219 |
DUSP3(MBP-his tagged) / VHR(MBP-his tagged)-50 |
AR09-P0006-50 |
Abfrontier |
50ug |
EUR 195 |
DUSP14(MBP-his tagged) / MKP6(MBP-his tagged)-50 |
AR09-P0007-50 |
Abfrontier |
50ug |
EUR 160 |
dual specificity phosphatase 12 (DUSP12)(MBP-his tagged)-50 |
AR09-P0017-50 |
Abfrontier |
50ug |
EUR 698 |
TGF a (1-50) (rat) |
H-5545.0050 |
Bachem |
50.0µg |
EUR 1118 |
Description: Sum Formula: C244H361N71O71S6; CAS# [89899-53-6] net |
TGF a (1-50) (rat) |
H-5545.1000 |
Bachem |
1.0mg |
EUR 16352 |
Description: Sum Formula: C244H361N71O71S6; CAS# [89899-53-6] net |
1-Ethynyl pyrene, 50 mg |
515B0 |
Lumiprobe |
50 mg |
EUR 52 |
Pyrene azide 1, 50 mg |
E1530 |
Lumiprobe |
50 mg |
EUR 501 |
Human IgG-RF stripper/Adsorbent (1 ml, sufficient for stripping 50 samples of 100 ul human serum/plasma) |
RFS-1 |
Alpha Diagnostics |
1 ml |
EUR 103 |
Cold Fusion Cloning Kit with Competent Cells (50 rxns) International Sales Only |
MC101A-1 |
SBI |
50 reactions |
EUR 1129 |
|
Phosphate Buffered Saline powder (PBS) pH 7.4, 50 l |
12-9425-1 |
Medicago |
50 l |
EUR 115 |
PLGA(50:50)(8K)-PEG-Mal |
abx085344-05kDa500mg |
Abbexa |
0.5 kDa; 500 mg |
EUR 1080 |
|
PLGA(50:50)(8K)-PEG-Mal |
abx085344-1kDa500mg |
Abbexa |
1 kDa; 500 mg |
EUR 1205 |
|
PLGA(50:50)(8K)-PEG-Mal |
abx085344-2kDa500mg |
Abbexa |
2 kDa; 500 mg |
EUR 1233 |
|
PLGA(50:50)(8K)-PEG-Mal |
abx085344-34kDa500mg |
Abbexa |
3.4 kDa; 500 mg |
EUR 1233 |
|
AXYPREP FRAGMENTSELECT-I KIT- 50 ML - 380 PREPS |
MAG-FRAG-I-50 |
CORNING |
1/pk |
EUR 659 |
Description: Bioscience Mag Beads; Magnetic Fragment Select |
RESERVOIR, POLYPROPYLENE, 50 ML, V-BOTTOM, STERILE, BULK |
RES-V-50-S |
CORNING |
5/pk |
EUR 112 |
Description: Reservoirs; Reservoirs - Axygen |
DiagNano Gold Nanorods, diameter 50 nm, absorption max 600 nm |
BR-50-600 |
Creative Diagnostics |
25 mL |
EUR 720 |
DiagNano Gold Nanorods, diameter 50 nm, absorption max 700 nm |
BR-50-700 |
Creative Diagnostics |
25 mL |
EUR 720 |
DiagNano Gold Nanorods, diameter 50 nm, absorption max 800 nm |
BR-50-800 |
Creative Diagnostics |
25 mL |
EUR 720 |
PTP4A3(MBP-his tagged) / PRL-3(MBP-his tagged)-50 |
AR09-P0008-50 |
Abfrontier |
50ug |
EUR 144 |
dual specificity phosphatase-like 15 (DUSP15)(MBP-his tagged)-50 |
AR09-P0018-50 |
Abfrontier |
50ug |
EUR 1154 |
dual specificity phosphatase-like 18 (DUSP18)(MBP-his tagged)-50 |
AR09-P0019-50 |
Abfrontier |
50ug |
EUR 1154 |
hSKRP1 mRNA for SKRP1 (NE1, DUSP19)(MBP-his tagged)-50 |
AR09-P0020-50 |
Abfrontier |
50ug |
EUR 1154 |
dual specificity phosphatase-like 21 (DUSP21)(MBP-his tagged)-50 |
AR09-P0021-50 |
Abfrontier |
50ug |
EUR 348 |
dual specificity phosphatase-like 26 (DUSP26)(MBP-his tagged)-50 |
AR09-P0022-50 |
Abfrontier |
50ug |
EUR 1154 |
protein tyrosine phosphatase zeta-polypeptide (PTPRZ)(MBP-his tagged)-50 |
AR09-P0025-50 |
Abfrontier |
50ug |
EUR 2080 |
M-phase inducer phosphatase 3 (CDC25C)(MBP-his tagged)-50 |
AR09-P0031-50 |
Abfrontier |
50ug |
EUR 1154 |
SureSeal S Sterile Microtube, 1.5mL, packed in self-standing bags of 50, 10 bags/pk |
C2000-50 |
MTC Bio |
500/pack |
EUR 63.16 |
Description: Micro Centrifuge Tubes |
100 bp DNA Ladder Plus, ready-to-use, 50 ug, 0.5 ug per lane |
Z6030001-1 |
Biochain |
100 lanes |
EUR 109 |
The aim of the present document from the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) and the Italian Society of Allergological, Occupational and Environmental Dermatology (SIDAPA) is to provide updated information to all physicians involved in diagnosis and management of urticaria and angioedema.