Immune checkpoint inhibitors (ICIs) are a promising advance within the therapy of sufferers with lung most cancers. Nonetheless, every ICI has been examined with an independently designed companion diagnostic assay that’s primarily based on a singular antibody. Consequently, the completely different trial-validated programmed demise ligand 1 (PD-L1) immunohistochemistry (IHC) assays shouldn’t be thought of interchangeable. Our intention was to check the efficiency of every out there PD-L1 antibody for its skill to precisely measure PD-L1 expression and to analyze the potential of harmonization throughout antibodies by means of using a brand new speedy IHC system, which makes use of noncontact alternating present (AC) mixing to attain extra secure staining.
First, 58 resected non-small cell lung most cancers (NSCLC) specimens had been stained utilizing three PD-L1 IHC assays (28-8, SP142, and SP263) to evaluate the harmonization achieved with AC mixing IHC. Second, specimens from 27 sufferers receiving ICIs for postoperative recurrent NSCLC had been stained utilizing the identical IHC technique to check the scientific efficiency of ICIs to PD-L1 scores. All sufferers obtained a tumor proportion rating (TPS) with the 22C3 companion diagnostic check.
Higher staining was achieved with the brand new AC mixing IHC technique than the traditional IHC in PD-L1-positive instances, and the interchangeability of some combos of assays was elevated in PD-L1-positive. As well as, AC mixing IHC offered extra acceptable general response charges for ICIs in all assays. Sixteen out of 85 tumors confirmed constructive staining representing 5% of FB tumors, 24% of CCS tumors and 47% of FM. In FB and CCS tumors, constructive staining was primarily encountered in atypical intraepidermal melanocytic proliferations and spitzoid neoplasms. The specificity of constructive PRAME staining was 95% and its concordance with the ultimate diagnostic interpretation was 75%.
Impression of Preanalytical Components on the Measurement of Tumor Tissue Biomarkers Utilizing Immunohistochemistry
Evaluation of formalin-fixed paraffin-embedded (FFPE) tissue by immunohistochemistry (IHC) is commonplace in scientific and analysis laboratories. Nonetheless, reviews recommend that IHC outcomes might be compromised by biospecimen preanalytical elements. The Nationwide Most cancers Institute’s Biospecimen Preanalytical Variables Program performed a scientific research to look at the potential results of delay to fixation (DTF) and time in fixative (TIF) on IHC utilizing 24 most cancers biomarkers. Variations in IHC staining, relative to controls with a DTF of 1 hr, had been noticed in FFPE kidney tumor specimens after a DTF of ≥2 hr.
Reductions in H-score and/or staining depth had been noticed for c-MET, p53, PAX2, PAX8, pAKT, and survivin, whereas will increase had been noticed for RCC1, EGFR, and CD10. Extended TIF of 72 hr resulted in considerably lowered H-scores of CD44 and c-Met in kidney tumor specimens, in contrast with controls with 12-hr TIF. An elevated likelihood of altered staining depth attributable to DTF was noticed for 9 antigens, whereas for extended TIF an elevated likelihood was noticed for one antigen.
Outcomes reported right here and elsewhere throughout tumor sorts and antigens assist limiting DTF to ≤1 hr when attainable and fixing tissues in formalin for 12-24 hr to keep away from confounding results of those preanalytical elements on IHC. The persistent an infection of high-risk human papillomavirus (HR-HPV) is among the most typical causes of cervical most cancers worldwide, and HPV kind 58 (HPV58) is the third most typical HPV kind in japanese Asia. The E7 oncoprotein is constitutively expressed in HPV58-associated cervical most cancers cells and performs a key function throughout tumorigenesis. This research aimed to evaluate the HPV58 E7 protein expression within the tissues of cervical most cancers and cervical intraepithelial neoplasia (CIN).
NKX3.1 immunohistochemistry is very particular for the prognosis of mesenchymal chondrosarcomas: expertise within the Australian inhabitants
Mesenchymal chondrosarcoma (MC) is a uncommon sarcoma that usually arises in adolescents and younger adults and characteristically harbours a HEY1-NCOA2 gene fusion. A current research has proven that NKX3.1 immunohistochemistry (IHC) is very particular and delicate in MCs. NKX3.1 is a nuclear marker expressed in prostatic tissue and is broadly utilized in most laboratories to find out prostatic origin of metastatic tumours. Within the present research we investigated whether or not this stain can be utilized within the diagnostic workup of MC, as it could help in triaging instances for additional molecular testing, by assessing its expression in a cohort of MCs and in a large spectrum of sarcoma sorts.
Moreover, we aimed to elucidate if expression of NKX3.1 by MCs is expounded to androgen receptor (AR) expression. We recognized NKX3.1 constructive nuclear staining in 9 of 12 particular person sufferers of MC (n=20 of 25 samples when taking into consideration separate episodes). 4 of the 5 unfavorable specimens had been beforehand subjected to acid-based decalcification. NKX3.1 was unfavorable in 536 samples from 16 non-MC sarcomas derived from largely tissue microarrays (TMAs). Total, we recognized 80% sensitivity and 100% specificity for NKX3.1 IHC in MCs.
) Immunohistochemistry Kit (OKRA00037) |
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| OKRA00037 | Aviva Systems Biology | 1 kit | EUR 805 |
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Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
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) Immunohistochemistry Kit (OKRA00038) |
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| OKRA00038 | Aviva Systems Biology | 1 kit | EUR 805 |
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Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
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) Immunohistochemistry Kit (OKRA00039) |
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| OKRA00039 | Aviva Systems Biology | 1 kit | EUR 805 |
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Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
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) Immunohistochemistry Kit (OKRA00040) |
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| OKRA00040 | Aviva Systems Biology | 1 kit | EUR 805 |
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Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
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 BrdU/ Rat BrdU ELISA Kit |
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| ELA-E1336r | Lifescience Market | 96 Tests | EUR 886 |
 Brdu |
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| 20-abx082348 | Abbexa |
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 5-BrdU |
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| B3589-1000 | ApexBio | 1 g | EUR 142 |
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Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111. |
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5-BrdU |
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| B3589-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 113 |
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Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111. |
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5-BrdU |
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| B3589-500 | ApexBio | 500 mg | EUR 108 |
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Description: 5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111. |
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 anti-BrdU |
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| BROF-100T | ImmunoStep | 100 test | EUR 537.5 |
5-BrdU |
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| HY-15910 | MedChemExpress | 5g | EUR 497 |
 BRDU antibody |
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| 10R-6763 | Fitzgerald | 1 ml | EUR 402 |
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Description: Mouse monoclonal BRDU antibody |
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BRDU antibody |
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| 10R-7945 | Fitzgerald | 100 ug | EUR 370 |
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Description: Mouse monoclonal BRDU antibody |
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BRDU antibody |
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| 10R-B121a | Fitzgerald | 100 ug | EUR 445 |
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Description: Mouse monoclonal BRDU antibody |
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BRDU antibody |
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| 20R-BS001 | Fitzgerald | 250 ug | EUR 553 |
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Description: Sheep polyclonal BRDU antibody |
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BRDU antibody |
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| 10R-2321 | Fitzgerald | 1 mL | EUR 601 |
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Description: Mouse monoclonal BRDU antibody |
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BRDU antibody |
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| 10R-2356 | Fitzgerald | 1.5 mL | EUR 490 |
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Description: Mouse monoclonal BRDU antibody |
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BRDU antibody |
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| 20-BS17 | Fitzgerald | 250 ug | EUR 386 |
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Description: Sheep polyclonal BRDU antibody |
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 Human BrDU ELISA Kit |
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| EHB0693 | Abclonal | 96Tests | EUR 521 |
 Mouse BrdU ELISA Kit |
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| ELA-E1336m | Lifescience Market | 96 Tests | EUR 865 |
 Goat BrDU ELISA Kit |
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| EGTB0693 | Abclonal | 96Tests | EUR 521 |
 Canine BrDU ELISA Kit |
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| ECB0693 | Abclonal | 96Tests | EUR 521 |
 Chicken BrDU ELISA Kit |
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| ECKB0693 | Abclonal | 96Tests | EUR 521 |
 Bovine BrDU ELISA Kit |
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| EBB0693 | Abclonal | 96Tests | EUR 521 |
 Anserini BrDU ELISA Kit |
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| EAB0693 | Abclonal | 96Tests | EUR 521 |
 Rat BrDU ELISA Kit |
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| ERB0693 | Abclonal | 96Tests | EUR 521 |
 Rabbit BrDU ELISA Kit |
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| ERTB0693 | Abclonal | 96Tests | EUR 521 |
 Sheep BrDU ELISA Kit |
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| ESB0693 | Abclonal | 96Tests | EUR 521 |
 Porcine BrDU ELISA Kit |
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| EPB0693 | Abclonal | 96Tests | EUR 521 |
 Mouse BrDU ELISA Kit |
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| EMB0693 | Abclonal | 96Tests | EUR 521 |
 Monkey BrDU ELISA Kit |
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| EMKB0693 | Abclonal | 96Tests | EUR 521 |
 apo-B100/ Rat apo- B100 ELISA Kit |
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| ELA-E0603r | Lifescience Market | 96 Tests | EUR 886 |
 apo-A1/ Rat apo- A1 ELISA Kit |
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| ELA-E0604r | Lifescience Market | 96 Tests | EUR 886 |
 Apo-E/ Rat Apo- E ELISA Kit |
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| ELA-E0704r | Lifescience Market | 96 Tests | EUR 886 |
 Apo-E4/ Rat Apo- E4 ELISA Kit |
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| ELA-E1858r | Lifescience Market | 96 Tests | EUR 886 |
 CytoSelect BrdU Competitive ELISA Kit |
|||
| CBA-5098 | Cell Biolabs | 96 assays | EUR 543 |
 BrdU Cell Proliferation Assay Kit |
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| C0300-050 | GenDepot | 500 Assays | EUR 928 |
BrdU Cell Proliferation Assay Kit |
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| C0300-100 | GenDepot | 1000 Assays | EUR 1312 |
BrdU Cell Proliferation Assay Kit |
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| C0300-500 | GenDepot | 5000 Assays | EUR 4438 |
 Guinea Pig BrDU ELISA Kit |
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| EGB0693 | Abclonal | 96Tests | EUR 521 |
ELISA Kit) Human Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E1920HM-48T | GenAsia Biotech | 48T | EUR 289 |
Human Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E1920HM-96T | GenAsia Biotech | 96T | EUR 466 |
ELISA Kit ) Mouse Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E0163MS-48T | GenAsia Biotech | 48T | EUR 336 |
Mouse Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E0163MS-96T | GenAsia Biotech | 96T | EUR 534 |
ELISA Kit) Rat Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E0659RT-48T | GenAsia Biotech | 48T | EUR 317 |
Rat Bromodeoxyuridine(BrdU)ELISA Kit |
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| GA-E0659RT-96T | GenAsia Biotech | 96T | EUR 496 |
 Human Bromodeoxyuridine,BrdU ELISA Kit |
|||
| 201-12-1904 | SunredBio | 96 tests | EUR 440 |
|
|||
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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 Rat Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-01657R1 | ChemNorm | 96T | EUR 447 |
Rat Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-01657R2 | ChemNorm | 48T | EUR 296 |
 Mouse Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-02530M1 | ChemNorm | 96T | EUR 471 |
Mouse Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-02530M2 | ChemNorm | 48T | EUR 322 |
Human Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-04581H1 | ChemNorm | 96T | EUR 471 |
Human Bromodeoxyuridine,BrdU ELISA Kit |
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| CN-04581H2 | ChemNorm | 48T | EUR 322 |
BrdU Cell Proliferation Assay Kit |
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| K306-1000 | Biovision | EUR 974 | |
BrdU Cell Proliferation Assay Kit |
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| K306-200 | Biovision | EUR 392 | |
Human Bromodeoxyuridine(BrdU)ELISA Kit |
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| QY-E00749 | Qayee Biotechnology | 96T | EUR 400 |
Rat Bromodeoxyuridine(BrdU)ELISA Kit |
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| QY-E10993 | Qayee Biotechnology | 96T | EUR 361 |
ELISA Kit) Mouse Bromodeoxyuridine(BrdU)ELISA Kit |
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| QY-E20224 | Qayee Biotechnology | 96T | EUR 361 |
 anti- BrdU antibody |
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| FNab00952 | FN Test | 100µg | EUR 548.75 |
|
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Description: Antibody raised against BrdU |
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 Antibody) Bromodeoxyuridine (BrdU) Antibody |
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| abx000064-100ul | Abbexa | 100 ul | EUR 411 |
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Bromodeoxyuridine (BrdU) Antibody |
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| abx412356-50ug | Abbexa | 50 ug | EUR 509 |
|
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Bromodeoxyuridine (BrdU) Antibody |
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| abx414257-02mg | Abbexa | 0.2 mg | EUR 565 |
|
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Bromodeoxyuridine (BrdU) Antibody |
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| abx414259-01mg | Abbexa | 0.1 mg | EUR 439 |
|
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Bromodeoxyuridine (BrdU) Antibody |
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| abx414260-20ug | Abbexa | 20 ug | EUR 272 |
|
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Bromodeoxyuridine (BrdU) Antibody |
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| abx230952-100ug | Abbexa | 100 ug | EUR 509 |
|
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 Anti-BrdU Antibody |
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| A1284-100 | Biovision | EUR 398 | |
 BrdU Mouse mAb |
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| A1482-100ul | Abclonal | 100 ul | EUR 308 |
BrdU Mouse mAb |
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| A1482-200ul | Abclonal | 200 ul | Ask for price |
BrdU Mouse mAb |
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| A1482-20ul | Abclonal | 20 ul | Ask for price |
BrdU Mouse mAb |
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| A1482-50ul | Abclonal | 50 ul | EUR 223 |
 Antibody) BrdU (Bu20a) Antibody |
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| 48275-100ul | SAB | 100ul | EUR 333 |
BrdU (Bu20a) Antibody |
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| 48275-50ul | SAB | 50ul | EUR 239 |
 Anti-BrdU Purified |
|||
| 11-682-C025 | ExBio | 0.025 mg | EUR 108 |
Anti-BrdU Purified |
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| 11-682-C100 | ExBio | 0.1 mg | EUR 177 |
Anti-BrdU Purified |
|||
| 11-286-C025 | ExBio | 0.025 mg | EUR 108 |
Anti-BrdU Purified |
|||
| 11-286-C100 | ExBio | 0.1 mg | EUR 177 |
 Anti-BrdU PE |
|||
| 1P-682-T025 | ExBio | 25 tests | EUR 140 |
Anti-BrdU PE |
|||
| 1P-682-T100 | ExBio | 100 tests | EUR 240 |
) BRDU antibody (FITC) |
|||
| 61R-1900 | Fitzgerald | 1 ml | EUR 409 |
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Description: Mouse monoclonal BRDU antibody (FITC) |
|||
 Anti-BrdU antibody |
|||
| STJ22838 | St John's Laboratory | 100 µl | EUR 277 |
Anti-BrdU antibody |
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| STJ16101064 | St John's Laboratory | 100 µg | EUR 354 |
 STAT Universal Animal IHC KIT-small |
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| 329ANK-20 | Innovex | Small Kit | EUR 717 |
 STAT Universal Animal IHC KIT-large |
|||
| 329ANK-60 | Innovex | Large Kit | EUR 1088 |
 ApoBrdU-IHC DNA Fragmentation Assay Kit |
|||
| 55R-1398 | Fitzgerald | 50 assays | EUR 1086 |
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Description: DNA Fragmentation Assay Kit for use in the research laboratory |
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ApoBrdU-IHC DNA Fragmentation Assay Kit |
|||
| K2072-50 | ApexBio | 50 assays | EUR 835 |
ApoBrdU-IHC DNA Fragmentation Assay Kit |
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| K403-50 | Biovision | EUR 794 | |
 HiQ Block for IHC |
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| B3077-010 | GenDepot | 100ml | EUR 134 |
HiQ Block for IHC |
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| B3077-050 | GenDepot | 500ml | EUR 263 |
 Frit Kit |
|||
| FRIT-KIT | Next Advance | 1each | EUR 124 |
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Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool. |
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 Column Packing Kit |
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| PACK-KIT | Next Advance | 1pack | EUR 1035 |
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Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar. |
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 CytoSelect BrdU Cell Proliferation ELISA Kit |
|||
| CBA-251 | Cell Biolabs | 96 assays | EUR 531 |
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Description: The CytoSelect BrdU Cell Proliferation ELISA Kit detects BrdU incorporated into cellular DNA during cell proliferation using an anti-BrdU antibody. When cells are incubated in media containing BrdU, the pyrimidine analog is incorporated in place of thymidine into the newly synthesized DNA of proliferating cells. Once the labeling media is removed, the cells are fixed and the DNA is denatured in one step with a fix/denature solution (denaturation of the DNA is necessary to improve the accessibility of the incorporated BrdU for detection). Then an anti-BrdU mouse monoclonal antibody is added followed by an HRP conjugated secondary antibody to detect the incorporated BrdU. The magnitude of the absorbance for the developed color is proportional to the quantity of BrdU incorporated into cells and can be directly correlated to cell proliferation. |
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) APO-DIRECTTM Kit (OKTA00007) |
|||
| OKTA00007 | Aviva Systems Biology | KIT | EUR 585 |
|
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity: |
|||
) APO-BrdUTM Kit (OKTA00008) |
|||
| OKTA00008 | Aviva Systems Biology | KIT | EUR 585 |
|
Description: Description of target: ;Species reactivity: ;Application: FC;Assay info: ;Sensitivity: |
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 PCR Mycoplasma Detection Kit |
|||
| M034-Kit | TOKU-E | Kit | EUR 266 |
 BrdU ELISA Kit| Rat Bromodeoxyuridine ELISA Kit |
|||
| EF018146 | Lifescience Market | 96 Tests | EUR 689 |
 Conjugated Antibody) BrdU (Bu20a) Conjugated Antibody |
|||
| C48275 | SAB | 100ul | EUR 397 |
(BRD469) Antibody) BrdU (Bromodeoxyuridine)(BRD469) Antibody |
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| BNUM0469-50 | Biotium | 50uL | EUR 395 |
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Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD469), 1mg/mL |
|||
(BRD494) Antibody) BrdU (Bromodeoxyuridine)(BRD494) Antibody |
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| BNUM0494-50 | Biotium | 50uL | EUR 395 |
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Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD494), 1mg/mL |
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(BU20a) Antibody) BrdU (Bromodeoxyuridine)(BU20a) Antibody |
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| BNUM0522-50 | Biotium | 50uL | EUR 395 |
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Description: Primary antibody against BrdU (Bromodeoxyuridine)(BU20a), 1mg/mL |
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BrdU (Bromodeoxyuridine)(BRD469) Antibody |
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| BNUB0469-100 | Biotium | 100uL | EUR 209 |
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Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD469), Concentration: 0.2mg/mL |
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BrdU (Bromodeoxyuridine)(BRD469) Antibody |
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| BNUB0469-500 | Biotium | 500uL | EUR 458 |
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Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD469), Concentration: 0.2mg/mL |
|||
BrdU (Bromodeoxyuridine)(BRD494) Antibody |
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| BNUB0494-100 | Biotium | 100uL | EUR 209 |
|
Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD494), Concentration: 0.2mg/mL |
|||
BrdU (Bromodeoxyuridine)(BRD494) Antibody |
|||
| BNUB0494-500 | Biotium | 500uL | EUR 458 |
|
Description: Primary antibody against BrdU (Bromodeoxyuridine)(BRD494), Concentration: 0.2mg/mL |
|||
BrdU (Bromodeoxyuridine)(BU20a) Antibody |
|||
| BNUB0522-100 | Biotium | 100uL | EUR 209 |
|
Description: Primary antibody against BrdU (Bromodeoxyuridine)(BU20a), Concentration: 0.2mg/mL |
|||
BrdU (Bromodeoxyuridine)(BU20a) Antibody |
|||
| BNUB0522-500 | Biotium | 500uL | EUR 458 |
|
Description: Primary antibody against BrdU (Bromodeoxyuridine)(BU20a), Concentration: 0.2mg/mL |
|||
 Antibody (FITC)) Bromodeoxyuridine (BrdU) Antibody (FITC) |
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| abx414258-50ug | Abbexa | 50 ug | EUR 342 |
|
|||
Bromodeoxyuridine (BrdU) Antibody (FITC) |
|||
| abx201100-100tests | Abbexa | 100 tests | EUR 620 |
|
|||
 BCIP/NBT Solution for IHC |
|||
| B3007-005 | GenDepot | 50ml | EUR 134 |
BCIP/NBT Solution for IHC |
|||
| B3007-010 | GenDepot | 100ml | EUR 188 |
BCIP/NBT Solution for IHC |
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| B3007-050 | GenDepot | 500ml | EUR 475 |
 IHC Enzyme Antigen Retrieval Reagent |
|||
| AR0022 | BosterBio | 50mL (for 500-750 assays) | EUR 106 |
 BCIP-NBT Dye for IHC |
|||
| G447 | ABM | 250 ml | EUR 254 |
 Universal IHC Diluent/Blocker/Stabilizer |
|||
| 85R-1021 | Fitzgerald | 1 liter | EUR 692 |
|
Description: Universal Diluent/Blocker/Stabilizer for use in IHC |
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) EMA antibody (Prediluted for IHC) |
|||
| 75R-1002 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal EMA antibody (Prediluted for IHC) |
|||
) hCG antibody (Prediluted for IHC) |
|||
| 75R-1005 | Fitzgerald | 7 ml | EUR 244 |
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Description: Mouse monoclonal hCG antibody (Prediluted for IHC) |
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) EpCAM antibody (Prediluted for IHC) |
|||
| 75R-1014 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal EpCAM antibody (Prediluted for IHC) |
|||
) p53 antibody (Prediluted for IHC) |
|||
| 75R-1015 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal p53 antibody (Prediluted for IHC) |
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) PCNA antibody (Prediluted for IHC) |
|||
| 75R-1016 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal PCNA antibody (Prediluted for IHC) |
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) S100 antibody (Prediluted for IHC) |
|||
| 75R-1017 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal S100 antibody (Prediluted for IHC) |
|||
) TSH antibody (Prediluted for IHC) |
|||
| 75R-1019 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal TSH antibody (Prediluted for IHC) |
|||
) Thyroglobulin antibody (Prediluted for IHC) |
|||
| 75R-1020 | Fitzgerald | 7 ml | EUR 225 |
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Description: Mouse monoclonal Thyroglobulin antibody (Prediluted for IHC) |
|||
) NSE antibody (Prediluted for IHC) |
|||
| 75R-1023 | Fitzgerald | 7 ml | EUR 232 |
|
Description: Mouse monoclonal NSE antibody (Prediluted for IHC) |
|||
) Ferritin antibody (Prediluted for IHC) |
|||
| 75R-1026 | Fitzgerald | 7 ml | EUR 187 |
|
Description: Rabbit polyclonal Ferritin antibody (Prediluted for IHC) |
|||
) Vimmentin antibody (Prediluted for IHC) |
|||
| 75R-1027 | Fitzgerald | 7 ml | EUR 187 |
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Description: Rabbit polyclonal Vimmentin antibody (Prediluted for IHC) |
|||
) Fibronectin antibody (Prediluted for IHC) |
|||
| 75R-1028 | Fitzgerald | 7 ml | EUR 187 |
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Description: Rabbit polyclonal Fibronectin antibody (Prediluted for IHC) |
|||
) CRP antibody (Prediluted for IHC) |
|||
| 75R-1029 | Fitzgerald | 7 ml | EUR 187 |
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Description: Rabbit polyclonal CRP antibody (Prediluted for IHC) |
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The sensitivity elevated to 95.2% when acid-based decalcified specimens had been excluded from the evaluation. No correlation between NKX3.1 expression and AR IHC was recognized. In abstract, our findings point out that NKX3.1 nuclear positivity is very delicate and particular for MC, offered that ethylenediaminetetraacetic acid (EDTA)-based quite than acid-based decalcification is used for pattern processing. NKX3.1 IHC in the precise scientific and histopathological setting can doubtlessly be ample for the prognosis of MC, reserving molecular affirmation just for equivocal instances.
Automated TTF-1 Immunohistochemistry Assay for the Differentiation of Lung Adenocarcinoma Versus Lung Squamous Cell Carcinoma
)
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 5mg Substrate Tabs)
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, 2-component system, 70ml)
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